Have you ever wondered why a medication that works perfectly for your neighbor has no effect on you -- or worse, causes side effects? The answer often lies in your genes.
What Is Pharmacogenomics?
Pharmacogenomics studies how genetic variation affects drug response. Specific gene variants can alter how your body metabolizes medications, affecting both efficacy and safety.
Common Examples
- Warfarin: CYP2C9 and VKORC1 variants affect dosing by up to 5x
- Codeine: CYP2D6 ultra-rapid metabolizers convert to morphine too quickly, risking overdose
- Clopidogrel: CYP2C19 poor metabolizers get reduced antiplatelet effect